Neuropsychological Performance in Long-term Cannabis Users
Harrison G. Pope, Jr, MD; Amanda J. Gruber, MD; James I. Hudson, MD, SM; Marilyn A. Huestis, PhD; Deborah Yurgelun-Todd, PhD
Arch Gen Psychiatry. 2001;58:909-915.
Comment From the PDF
"In a study of cognitive function among long-term heavy cannabis users, we found deficits on memory of word lists, detectable at least 7 days after discontinuing the drug and related to initial urinary concentrations of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol. After 28 days of abstinence, however, users showed virtually no significant differences from control subjects on a battery of 10 neuropsychological tests. Former heavy users, who had consumed little or no cannabis in the 3 months before testing, showed no significant differences from control subjects on any of these tests on any of the testing days. The paucity of significant differences between the cannabis and control groups at day 28, together with the lack of significant associations between test scores and lifetime cannabis consumption, suggests that cannabis-associated cognitive deficits may be reversible phenomena associated with recent drug exposure, rather than irreversible phenomena associated with cumulative lifetime use."
From the Biological Psychiatry Laboratory, McLean Hospital, and the Department of Psychiatry, Harvard Medical School, Belmont, Mass (Drs Pope, Gruber, Hudson, and Yurgelun-Todd); and the Intramural Research Program, National Institute on Drug Abuse, Baltimore, Md (Dr Huestis).
Next month I'll be straight, and the anti-grass brigade will still be brain-fucked.
(Disclaimer: The safe use of Marijuana is by no means proven, especially (obviously) for young or malfunctioning minds. I do not mean to imply that it is safe, save this "long-term brain damage" bit. Lack of reputable research is the Pot Nanny's last line of defense.)
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